The primary constituents of Thorne's grape seed extract are oligomeric proanthocyanidins (OPCs). OPCs have strong free-radical scavenging (antioxidant) ability, resulting in inhibition of oxidative damage and protection of blood vessels and other tissues.* OPCs have been shown to protect vascular endothelial cells from oxidative damage and appear to strengthen the resistance of cell membranes to injury and impairment.* OPCs also can bind copper and iron, thereby reducing their oxidative effects.* OPC-100 contains Leucoselect Phytosome®, which have demonstrated in studies to reduce the oxidation of LDL-cholesterol in heavy smokers, and decrease oxidative stress in diabetics and in healthy individuals after a fatty meal.*
Evidence suggests OPCs enhance the cross-linkage of collagen in skin and other connective tissues.* OPCs have also been shown to decrease capillary permeability, which can be manifest as decreased bruising.* For example, clinical studies demonstrate reduced swelling and improved resolution of sports injuries in athletes who were given OPCs prior to a sporting event.*
A clinical study of 10 healthy volunteers analyzing the effect of OPC supplementation on biomarkers of oxidative stress found significantly increased levels of the antioxidant alpha-tocopherol in red blood cell membranes.*
In a randomized human trial, young healthy volunteers received 300 mg of Leucoselect phytosome daily or a placebo. Antioxidant activity was measured at multiple time-points during days one and five. Within 30 minutes after administration on day one, the antioxidant activity measured by "total radical-trapping antioxidant parameter" (TRAP) was significantly elevated compared to placebo.*
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*FDA Disclaimer: The information about this product and statements made are provided by the manufacturer, except customer reviews which are not evaluated. See www.thorne.com for information about the relationship between this product and any claims made. Results may vary from person to person based on body size and other factors, and the effectiveness is not guaranteed for you. Always seek the advice of your healthcare professional about taking dietary, nutritional, herbal or homeopathic supplements.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
O.P.C.-100 contains grape seed phytosome - a plant extract complexed with phospholipids, which are derived from soy. Phospholipids contain no soy protein. There are no other soy-based ingredients in O.P.C.-100.
PREGNANCY WARNING
If pregnant, consult your health professional before using this product.
INTERACTIONS
There are no known adverse interactions or contraindications at publication date.