Thorne offers melatonin in both 3 mg (Melatonin-3) and 5 mg (Melatonin-5) capsules. Melatonin, the primary hormone of the pineal gland, is a powerful "chronobiotic" that helps maintain the body's normal circadian rhythms.* In individuals who have difficulty sleeping or who have altered circadian rhythms because of jet lag or night shift work, melatonin supplementation promotes the resynchronization of this cycle.* Supplementation can also benefit those whose difficulty sleeping is caused by the aging-related decrease in the body's ability to synthesize melatonin from the amino acid tryptophan.* Research indicates melatonin exerts its sleep-promoting efficacy by decreasing the amount of time needed to fall asleep, by promoting the ability to stay asleep, and by enhancing the depth of sleep.*
Melatonin administration from 0.3 mg to 5.0 mg has been shown to exert a sedative-like effect.* When supplemented prior to the onset of the body's normal melatonin secretion, even a low amount of melatonin can promote sleep.* Melatonin apparently enhances the effect of gamma-aminobutyric acid (GABA) via direct interaction with GABA receptors, thus resulting in relaxation.* Thorne's Melaton-3 supplies three mg of melatonin in each capsule, and Melaton-5 supplies 5 mg per capsule and is used when a higher amount of melatonin is desired. Melatonin also has significant antioxidant activity.* Adequate melatonin levels have been reported to be a positive factor in cardiovascular, neuroendocrine, GI, and bone health.*
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*FDA Disclaimer: The information about this product and statements made are provided by the manufacturer, except customer reviews which are not evaluated. See www.thorne.com for information about the relationship between this product and any claims made. Results may vary from person to person based on body size and other factors, and the effectiveness is not guaranteed for you. Always seek the advice of your healthcare professional about taking dietary, nutritional, herbal or homeopathic supplements.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY WARNING
If pregnant or nursing, do not use this product.
INTERACTIONS
Because melatonin may potentiate the effect of blood-thinning medications, Melaton-5 should be used with caution or avoided in individuals on anticoagulant therapy or prior to surgery.